Helping women stop bladder leaks and live freely is at the heart of what we do -and we have compelling evidence to support it. Seven clinical trials and extensive consumer research demonstrate Contrelle’s effectiveness in stopping
leaks and significantly improving quality of life.This combination of scientificrigour and real-world validation underpins everything we do.3
leaks stopped or reduced1
dry2
improved quality of life2
find comfortable6
become more physically active3
Clinical Trial Results
Six clinical trials have tested Contrelle’s effectiveness by measuring bladder leakage with and without the device in place, using incontinence pad weight as a
measurement. All six trials showed statistically significant success, with up to 95% of women reporting a benefit and 68% becoming completely dry.1
Long-Term Benefits
A seventh clinical trial looked at women using Contrelle over 12 months and found an additional benefit – long-term reduction in bladder leakage, even when the device wasn’t in place. This suggests that prolonged use may help retrain your pelvic floor muscles.1
Safety Profile
Across all our clinical trials, there were no pH changes or effects on vaginal flora, and there have been no reported cases of Toxic Shock Syndrome (TSS).2
Real Women, Real Results
Our consumer research confirms what the trials show. 96% of women saw a benefit from using Contrelle, and 82% became either completely dry or experienced greatly reduced leaks when wearing the device. What’s more, 96% found Contrelle comfortable, and three-quarters found it easy to use.6
Contrelle delivers proven results.
Numerous research studies highlight the devastating impact bladder leaks have on women’s physical and mental health5 . That’s why Contrelle’s effectiveness is truly life-changing. Our testimonials tell the story, but the clinical data and consumer research prove it.
Life-Changing Improvements
Clinical trials demonstrated that 60% of women became more active when using Contrelle, with a four fold improvement in quality of life3. Our consumer research reveals even more detail about this transformation:6
Confidence Restored
Most importantly, the results show that women now feel confident during everyday activities:
Contrelle doesn’t just stop leaks – it restores the freedom to live life on your terms.
Contrelle stands alone as the only bladder support backed by multiple clinical trials and extensive UK-based consumer research. More importantly, we’re the only device to deliver such consistently positive results and dramatic improvements in quality of life.
We’re committed to continuously growing the clinical evidence for Contrelle Activgard-showing how it can reduce or stop bladder leaks in women with stress urinary incontinence, and exploring its potential to help with other conditions.
One of the largest clinical trials in Europe
The Contrelle Activgard team is leading one of Europe’s largest trials in women’s bladder leakage, to understand how Contrelle can improve everyday life while also helping to support and educate healthcare professionals.
Conducted across NHS hospitals
This major trial is being carried out in partnership with several UK NHS hospitals, including, Southampton, Basingstoke, Frimley and Ashford & St Peter’s.
A separate study: Contrelle + pelvic floor exercises
A further innovative study is also underway with the UK’s centre for women’s health research, supported by NICE. This research is looking in detail at outcomes when Contrelle is used alongside pelvic floor exercises.
Additional NHS evaluations
Alongside these two studies, further NHS clinical evaluations are in progress to explore the additional benefits and longer-term outcomes of using Contrelle.
Clinically proven to be safe and effective.2
1Thyssen HH, Lose G. Long term efficacy and safety of a disposable vaginal device (continence guard) in the treatment of female stress incontinence. Int Urogynecol J Pelvic Floor Dysfunct. 1997;8(3):130-2
2 Lone Mouritsen. Effect of vaginal devices on bladder neck mobility in stress incontinent women, Departmentof Obstretrics and Gynecology, Gentofte Hospital, University of Copenhagen, Denmark Acta Obstetricia et Gynecologica Scandinavica 2001 80: 428-431
3 Sander P, Thyssen H, Lose G, Andersen JT. Effect of a vaginal device on quality of life of women with urinary stress incontinence. Obstet Gynecol. 1999 Mar;93(3):407-11.
5 Vigod and Stewart (2006): Major Depression and Urinary Incontinence.
6 Based on a customer survey of 140 trialists. Nov 2023- Sept 2024
